abstract：OBJECTIVES:To identify errors in surgical pathology practice that lead to malpractice claims, and to define the frequency and severity of pathology malpractice claims and discuss the implications. DESIGN:Three hundred seventy-eight pathology malpractice claims reported to The Doctors Company of Napa, Calif, between 19...

journal_title：Archives of pathology & laboratory medicine

authors： Troxel DB

更新日期：2005-10-01 00:00:00

abstract：CONTEXT:Myelodysplastic syndromes (MDSs) are clonal stem cell diseases characterized by ineffective hematopoiesis, multilineage dysplasia, and peripheral cytopenias with normocellular or hypercellular marrow. They represent a heterogeneous group of disorders with a varied spectrum of clinical, morphologic, biologic, an...

journal_title：Archives of pathology & laboratory medicine

authors： Nishino HT,Chang CC

更新日期：2005-10-01 00:00:00

abstract：CONTEXT:CDX2, a critical nuclear transcription factor for intestinal development, is expressed in intestinal epithelium and adenocarcinomas. OBJECTIVES:To determine if CDX2 is a useful marker for intestinal-type differentiation and to correlate tumor histology with CDX2 staining in colorectal adenocarcinomas. DESIGN:...

journal_title：Archives of pathology & laboratory medicine

authors： De Lott LB,Morrison C,Suster S,Cohn DE,Frankel WL

更新日期：2005-09-01 00:00:00

abstract：:A 14-year-old adolescent girl presented with severe congestive heart failure, progressive throughout 3 months. A precordial thrill, machinery-like murmur, and right bundle branch block were noted. Death occurred despite digitalis and diuretic therapy and removal of pleural and ascitic fluid. The autopsy revealed 2 mul...

journal_title：Archives of pathology & laboratory medicine

authors： Lucey BP,Thomas CB,Hutchins GM

更新日期：2005-09-01 00:00:00

abstract：CONTEXT:Workup for prolonged prothrombin time (PT) and activated partial thromboplastin time (PTT) is a frequent referral to a Hematology and Coagulation Laboratory. Although the workup should be performed in a timely and cost-effective manner, the complete laboratory assessment of the coagulation state has not been st...

journal_title：Archives of pathology & laboratory medicine

authors： Acosta M,Edwards R,Jaffee IM,Yee DL,Mahoney DH,Teruya J

更新日期：2005-08-01 00:00:00

abstract：:We report a primary intraocular T-cell-rich large B-cell lymphoma in a 57-year-old woman who underwent 3 diagnostic vitrectomies for a presumed diagnosis of panuveitis. She developed no light perception in the left eye and underwent enucleation. Histopathologic and immunohistochemical studies on the enucleated globe d...

journal_title：Archives of pathology & laboratory medicine

authors： Cummings TJ,Stenzel TT,Klintworth G,Jaffe GJ

更新日期：2005-08-01 00:00:00

abstract：CONTEXT:Pretransfusion testing of whole blood and red blood cell recipients is regulated by the federal government under the authority of the Clinical Laboratory Improvement Amendments of 1988. Regulated tests include determination of ABO group, Rh D type, antibody detection, antibody identification, and crossmatching....

journal_title：Archives of pathology & laboratory medicine

authors： Shulman IA,Maffei LM,Downes KA

更新日期：2005-08-01 00:00:00

abstract：:Whipple disease is a chronic, relapsing, and multisystem disease. It presents a diagnostic challenge for both clinicians and pathologists. Recent advances in isolation and culture have identified the organism responsible for the disease to be a member of the order Actinomycetes designated Tropheryma whipplei. Several ...

journal_title：Archives of pathology & laboratory medicine

authors： Muir-Padilla J,Myers JB

更新日期：2005-07-01 00:00:00

abstract：:Periosteal osteoblastoma is an extremely rare bone-forming neoplasm located on the surface of cortical bone. Of the fewer than 30 cases of periosteal osteoblastomas found in the literature, 2 have been reported to be located in cranial bone, and these have not been documented in detail with clinical history, radiograp...

journal_title：Archives of pathology & laboratory medicine

authors： Lin YC,Commins DL,Fedenko AN,Pinsky GS

更新日期：2005-06-01 00:00:00

abstract：CONTEXT:Expert opinion is often used as a gold standard for gynecologic cytology in the evaluation of new technologies, in the legal setting, and in the validation of cases for use in educational programs and proficiency testing. However, the reliability of expert opinion alone in selecting slides of a specific cytodia...

journal_title：Archives of pathology & laboratory medicine

authors： Renshaw AA,Wang E,Mody DR,Wilbur DC,Davey DD,Colgan TJ,Cytopathology Resource Committee, College of American Pathologists.

更新日期：2005-05-01 00:00:00

abstract：CONTEXT:The American Board of Medical Specialties Maintenance of Certification (MOC) process will become effective in 2006. The College of American Pathologists (CAP) Education Committee defined pathology-specific competencies within MOC categories and used data from a survey of pathologists to create education courses...

journal_title：Archives of pathology & laboratory medicine

authors： Hammond ME,Filling CM,Neumann AR,Homburger HA,Education Committee, College of American Pathologists.

更新日期：2005-05-01 00:00:00

abstract：CONTEXT:Dysregulation of mediators of apoptosis is associated with carcinogenesis. For biliary duct cancers, p53 gene mutation is an important contributor to carcinogenesis. Mutations in the p53 gene affect transcription of the Fas gene, resulting in lack of Fas expression on cell membrane. It has been previously shown...

journal_title：Archives of pathology & laboratory medicine

authors： Jhala NC,Vickers SM,Argani P,McDonald JM

更新日期：2005-04-01 00:00:00

abstract：:Natural killer cell and cytotoxic T-cell lymphomas are frequently difficult to distinguish because they share many common features, and yet it is important to make an accurate diagnosis because their prognoses differ. We report an unusual case of a white man with a CD56-positive T-cell lymphoma in the ileum. The histo...

journal_title：Archives of pathology & laboratory medicine

authors： Frank MC,Bono E,Sun T

更新日期：2005-04-01 00:00:00

abstract：CONTEXT:Perineural invasion and vascular invasion may be adverse prognostic factors in patients with oral cavity squamous cell carcinoma. However, the incidence of perineural and vascular invasion varies in the literature, and the use of immunohistochemistry to enhance their detection has not been evaluated in oral cav...

journal_title：Archives of pathology & laboratory medicine

authors： Kurtz KA,Hoffman HT,Zimmerman MB,Robinson RA

更新日期：2005-03-01 00:00:00

abstract：:Malignant deciduoid mesothelioma, a rare phenotype of epithelioid mesothelioma, arises more commonly from the peritoneum of young women, but it is also reported in the pleura of elderly people. We report a case of malignant deciduoid mesothelioma that occurred in a 41-year-old woman after cesarean section and was init...

journal_title：Archives of pathology & laboratory medicine

authors： Mourra N,de Chaisemartin C,Goubin-Versini I,Parc R,Flejou JF

更新日期：2005-03-01 00:00:00

abstract：:Rhabdoid tumor of the thyroid gland is a very rare neoplasm, characterized by significant metastatic potential. All of the 6 cases reported in the recent literature had poor outcomes. We report an additional case involving, to our knowledge, the oldest patient reported so far. A 67-year-old woman had a nodular goiter ...

journal_title：Archives of pathology & laboratory medicine

authors： Lai ML,Faa G,Serra S,Senes G,Daniele GM,Boi F,Mariotti S,Beauchemin M,Asa SL

更新日期：2005-03-01 00:00:00

abstract：CONTEXT:Relatively little is known about estrogen receptor (ER) expression in papillary urothelial carcinoma (PUC) of the bladder. Greater understanding of this feature of PUCs could aid with the treatment and identification of the origin of metastases, particularly with relation to the morphologically similar entity o...

journal_title：Archives of pathology & laboratory medicine

authors： Croft PR,Lathrop SL,Feddersen RM,Joste NE

更新日期：2005-02-01 00:00:00

abstract：:Primary synovial sarcoma rarely originates in the renal parenchyma. When this occurs, origin of this unusual tumor type has been the subject of debate in the literature, with a suggestion that previously reported cases may be more correctly described as renal cell carcinoma with sarcomatoid dedifferentiation. Synovial...

journal_title：Archives of pathology & laboratory medicine

authors： Shannon BA,Murch A,Cohen RJ

更新日期：2005-02-01 00:00:00

abstract：:A 47-year-old white man presented for evaluation of a complex right renal mass. He had a history of human immunodeficiency virus. Cervical lymph node biopsy had revealed small lymphocytic lymphoma. Computed tomographic scan disclosed diffuse mesenteric and retroperitoneal adenopathy consistent with chronic lymphocytic...

journal_title：Archives of pathology & laboratory medicine

authors： Iczkowski KA,Gapin TB,Wajsman Z

更新日期：2005-01-01 00:00:00

abstract：CONTEXT:Distinct human polyomavirus genotypes cause different diseases in patients with renal transplants: BK virus (BKV) causes tubulointerstitial nephritis and ureteral stenosis, whereas both JC virus (JCV) and BKV are responsible for hemorrhagic cystitis. These findings could result from a selective infection of kid...

journal_title：Archives of pathology & laboratory medicine

authors： Boldorini R,Veggiani C,Barco D,Monga G

更新日期：2005-01-01 00:00:00

abstract：CONTEXT:The pyrimidine nucleoside analog, cytosine arabinoside (Ara-C), is an effective therapeutic agent for acute leukemia. The phosphorylated triphosphate, cytosine arabinoside triphosphate, competes with deoxycytosine triphosphate as a substrate for incorporation into DNA. Once incorporated into DNA, it inhibits DN...

journal_title：Archives of pathology & laboratory medicine

authors： Zhang X,Kiechle FL

更新日期：2004-12-01 00:00:00

abstract：:Petrification of the auricle results in a rigid and immalleable ear. The etiology of such a finding is usually ectopic calcification. The condition has been associated with injurious processes, such as cold injury, and with various endocrinopathies, including Addison disease. In a significant number of cases, ossifica...

journal_title：Archives of pathology & laboratory medicine

authors： High WA,Larson MJ,Hoang MP

更新日期：2004-12-01 00:00:00

abstract：CONTEXT:Cervicography and oncogenic human papillomavirus (HPV) testing have been proposed for improving the accuracy of cervical cancer screening. OBJECTIVE:To examine whether cervicography and HPV testing can improve beyond chance the detection of cervical intraepithelial neoplasia (CIN) 2 or 3 in women with atypical...

journal_title：Archives of pathology & laboratory medicine

authors： Howard M,Sellors JW,Lytwyn A,Roth P,Mahony JB

更新日期：2004-11-01 00:00:00

abstract：:Angioimmunoblastic T-cell lymphoma is a nodal peripheral T-cell lymphoma that rarely involves the skin. We describe a 62-year-old Taiwanese man who developed a second relapse of angioimmunoblastic T-cell lymphoma with generalized erythroderma and numerous plaquelike and nodular lesions. Biopsy of the erythematous skin...

journal_title：Archives of pathology & laboratory medicine

authors： Huang CT,Chuang SS

更新日期：2004-10-01 00:00:00

abstract：:We report 2 cases of nonspecific postvaccinial dermatitis following smallpox vaccination. The patients presented with diffuse, pruritic, erythematous macules and papules 11 days (case 1) and 7 days (case 2) following routine smallpox vaccination. Biopsies of the lesions demonstrated spongiotic dermatitis without evide...

journal_title：Archives of pathology & laboratory medicine

authors： Gaertner EM,Groo S,Kim J

更新日期：2004-10-01 00:00:00

abstract：CONTEXT:There are 2 general types of assays measuring MUC1 gene-derived glycoprotein: assays for cancer antigen (CA) 15-3, which are sandwich assays, and assays for CA 27.29, which are competitive assays. These 2 types of assays measure slightly different parts of this tandem-repeat molecule. Across-method assay differ...

journal_title：Archives of pathology & laboratory medicine

authors： Klee GG,Schreiber WE

更新日期：2004-10-01 00:00:00

abstract：:We report the case of a 73-year-old man who presented with a 2- to 3-month history of epigastric discomfort and guaiac-positive stool. An upper gastrointestinal endoscopy revealed a diffuse erythematous nodular mucosa and submucosal thickening in the stomach. Diffuse mucosal nodularity was also found in the second por...

journal_title：Archives of pathology & laboratory medicine

authors： Tang Z,Jing W,Lindeman N,Harris NL,Ferry JA

更新日期：2004-09-01 00:00:00

abstract：:Although mucoepidermoid carcinoma is the most common primary malignancy of the salivary glands, the sclerosing morphologic variant of this tumor is extremely rare, with only 6 reported cases. As its name suggests, sclerosing mucoepidermoid carcinoma is characterized by an intense central sclerosis that occupies the en...

journal_title：Archives of pathology & laboratory medicine

authors： Fadare O,Hileeto D,Gruddin YL,Mariappan MR

更新日期：2004-09-01 00:00:00

abstract：CONTEXT:Impairment of venous outflow manifests as zone 3 sinusoidal dilatation and congestion (SDC) in liver biopsy. However, the finding of SDC is not specific for venous outflow impairment.Objectives.-To determine the specificity of SDC in liver biopsies for venous outflow impairment and to seek an explanation for SD...

journal_title：Archives of pathology & laboratory medicine

authors： Kakar S,Kamath PS,Burgart LJ

更新日期：2004-08-01 00:00:00

abstract：:Basal cell carcinoma arising from the nipple of the breast is an uncommon malignancy, with only a handful of cases reported in the literature. The diagnosis is, however, important because basal cell carcinoma in this location can mimic breast cancer, may behave aggressively, and there is a relative lack of consensus i...

journal_title：Archives of pathology & laboratory medicine

authors： Gupta C,Sheth D,Snower DP

更新日期：2004-07-01 00:00:00

abstract：CONTEXT:One of the major attributes of laboratory testing is cost. Although fully automated central laboratory glucose testing and semiautomated bedside glucose testing (BGT) are performed at most institutions, rigorous determinations of interinstitutional comparative costs have not been performed. OBJECTIVES:To compa...

journal_title：Archives of pathology & laboratory medicine

authors： Howanitz PJ,Jones BA,College of American Pathologists.

更新日期：2004-07-01 00:00:00

abstract：:We describe the case of a 31-week fetus who died in utero with an invasive retroperitoneal kaposiform hemangioendothelioma. This rare vascular neoplasm usually presents as a localized violaceous skin lesion in infants and behaves in a benign fashion; however, kaposiform hemangioendothelioma may present as an invasive ...

journal_title：Archives of pathology & laboratory medicine

authors： Martinez AE,Robinson MJ,Alexis JB

更新日期：2004-06-01 00:00:00

abstract：CONTEXT:The laboratory test turnaround times (TATs) that exceed the expectations of clinicians who order those tests, the so-called outlier test reporting rates, may be responsible for perceptions of inadequate laboratory service. OBJECTIVE:To monitor outlier test reporting rates for emergency department stat potassiu...

journal_title：Archives of pathology & laboratory medicine

authors： Novis DA,Walsh MK,Dale JC,Howanitz PJ,College of American Pathologists Q-Tracks.

更新日期：2004-06-01 00:00:00

abstract：CONTEXT:Since 1988, the College of American Pathologists has been offering materials for calibration verification coupled with the surveys for linearity, called the linearity (LN) surveys. OBJECTIVE:To determine whether successful completion of the College of American Pathologists LN surveys provides a benefit in term...

journal_title：Archives of pathology & laboratory medicine

authors： Kroll MH,Styer PE,Vasquez DA

更新日期：2004-05-01 00:00:00

abstract：:We report a case of gastric myeloid metaplasia in an 89- year-old woman with agnogenic myeloid metaplasia. The lesions were fortuitously discovered on upper endoscopy. The antral mucosa was thickened and polypoid, and on histologic examination contained immature granulocytes, megakaryocytes, and a few erythroblasts wi...

journal_title：Archives of pathology & laboratory medicine

authors： Chatelain D,Devendeville A,Rudelli A,Bruniau A,Geslin G,Sevestre H

更新日期：2004-05-01 00:00:00

abstract：CONTEXT:Although the cytologic features of squamous cell carcinoma in ThinPrep specimens are well known, whether these features are different in cases that are easily identified than in cases that are more difficult to identify is not known. OBJECTIVE:To determine the cytologic features of squamous cell carcinoma in T...

journal_title：Archives of pathology & laboratory medicine

authors： Renshaw AA,Dubray-Benstein B,Cobb CJ,Lozano RL,Neal MH,Prey M,Schulte MA,Gynecologic Cytology Committee, College of American Pathologists.

更新日期：2004-04-01 00:00:00

abstract：:This report describes a case of acute myeloid leukemia (subtype M1) with biphasic morphology. The bone marrow biopsy showed 2 distinct regions of blasts, one containing large cells and the other small cells. Morphometric and DNA ploidy analysis showed that the mean nuclear area and mean DNA index for the large cell re...

journal_title：Archives of pathology & laboratory medicine

authors： Imkie M,Davis MK,Persons DL,Cunningham MT

更新日期：2004-04-01 00:00:00

abstract：:We report a case of solitary fibrous tumor involving the spinal nerve root at the L1-L2 level in a 67-year-old man. The patient presented with lumbar pain and weakness in his right lower extremity. Histologically, the tumor was composed of a proliferation of monomorphous spindle cells in an abundant collagenous stroma...

journal_title：Archives of pathology & laboratory medicine

authors： Piana S,Putrino I,Cavazza A,Nigrisoli E

更新日期：2004-03-01 00:00:00

abstract：CONTEXT:Carcinoid tumor metastatic to the breast is uncommon and can closely mimic a mammary carcinoma. The differentiation of metastatic carcinoid tumor from primary breast tumor is important, however, owing to different clinical management and prognosis. OBJECTIVE:The purpose of this study was to describe 2 patients...

journal_title：Archives of pathology & laboratory medicine

authors： Mosunjac MB,Kochhar R,Mosunjac MI,Lau SK

更新日期：2004-03-01 00:00:00

abstract：:In cases of obscure gastrointestinal bleeding, when a source for blood loss is not apparent from examination of the colon and upper gastrointestinal tract, the small bowel usually becomes the focus of investigation. A tumor with interesting pathologic features was found in a patient who presented with recurrent episod...

journal_title：Archives of pathology & laboratory medicine

authors： Sass DA,Chopra KB,Finkelstein SD,Schauer PR

更新日期：2004-02-01 00:00:00